To restore normal function to the blood, Leukemic cells must be eliminated. Since they cannot be removed surgically, these cells are killed inside the body using various treatments that include chemotherapy.
One of the side effects of this treatment strategy is the unavoidable elimination of healthy cells. When healthy stem cells in the bone marrow are destroyed, the body can no longer create new blood cells on its own. Fortunately, stem cells from a donor’s bone marrow can be transplanted into the patient to help with this process. However, unlike blood transplants, there are thousands of HLA (Human Leukocyte Antigen) types. Because of this, the search for a match is expanded to a database containing the genetic makeup of millions of voluntary bone marrow donors.
The more potential donors there are, the higher the chance a match is found!